Molecular and Cellular Pharmacology, Vol 2, No 5 (2010)

Font Size:  Small  Medium  Large

MicroRNA-based Cancer Therapeutics: Big Hope From Small RNAs

Arun Bhardwaj, Seema Singh, Ajay P Singh

Abstract


Tremendous progress has been made during the last few years in identification of novel tumor-associated microRNAs and experimental validation of their cancer relevant gene targets. Indeed, these small non-coding RNAs are now known to modulate many biological pathways related to cancer progression, metastasis and therapy-resistance. Therefore, modulating miRNA functions may provide novel therapeutic opportunities for cancer treatment. This article reviews recent literature on the role of miRNAs in cancer with an emphasis on their potential as cancer therapeutics.


Full Text: PDF


LumiText Publishing, P.O. Box 774, Ellicott City, MD 21041 

Copyright © 2008 LumiText Publishing. All rights reserved.